Anti-CDK5RAP1 antibody (1-350) (STJ118289) STJ118289 上海玉博生物科技有限公司

Anti-CDK5RAP1 antibody (1-350) (STJ118289)

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产品名称：Anti-CDK5RAP1 antibody (1-350) (STJ118289)
产品型号：STJ118289
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-CDK5RAP1 antibody (1-350) (STJ118289)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CDK5RAP1 (1-350) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:100
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDK5RAP1
Gene ID:	51654
Uniprot ID:	CK5P1_HUMAN
Immunogen Region:	1-350
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CDK5RAP1 (NP_057492.2).
Immunogen Sequence:	MHPLQCVLQVQRSLGWGPLA SVSWLSLRMCRAHSSLSSTM CPSPERQEDGARKDFSSRLA AGPTFQHFLKSASAPQEKLS SEVEDPPPYLMMDELLGRQR KVYLETYGCQMNVNDTEIAW SILQKSGYLRTSNLQEADVI LLVTCSIREKAEQTIWNRLH QLKALKTRRPRSRVPLRIGI LGCMAERLKEEILNREKMVD ILAGPDAYRDLPRLLAVAES GQQAANVLLSLDETYADVM

Tissue Specificity	Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in neurons of central nervous tissue. Isoform 5: Mainly expressed in brain, placenta and testis. Isoform 6: High expression in placenta and lung.
Function	Methylthiotransferase that catalyzes the conversion of N6-(dimethylallyl)adenosine (i(6)A) to 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 (adjacent to the 3'-end of the anticodon) of four mitochondrial DNA-encoded tRNAs (Ser(UCN), Phe, Tyr and Trp). Essential for efficient and highly accurate protein translation by the ribosome. Specifically inhibits CDK5 activation by CDK5R1. Essential for efficient mitochondrial protein synthesis and respiratory chain.shows pathological consequences in mitochondrial disease.
Protein Name	Mitochondrial Trna Methylthiotransferase Cdk5rap1 Cdk5 Activator-Binding Protein C42 Cdk5 Regulatory Subunit-Associated Protein 1 Mt-Trna-2-Methylthio-N6-Dimethylallyladenosine Synthase Mt-Trna-N6-(Dimethylallyladenosine(37 Methylthiotransferase
Cellular Localisation	Mitochondrion
Alternative Antibody Names	Anti-Mitochondrial Trna Methylthiotransferase Cdk5rap1 antibody Anti-Cdk5 Activator-Binding Protein C42 antibody Anti-Cdk5 Regulatory Subunit-Associated Protein 1 antibody Anti-Mt-Trna-2-Methylthio-N6-Dimethylallyladenosine Synthase antibody Anti-Mt-Trna-N6-(Dimethylallyladenosine(37 Methylthiotransferase antibody Anti-CDK5RAP1 antibody Anti-C20orf34 antibody Anti-CGI-05 antibody Anti-HSPC167 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-CDK5RAP1 antibody (1-350) (STJ118289)