Anti-FIG4 antibody (608-907) (STJ117567) STJ117567 上海玉博生物科技有限公司

Anti-FIG4 antibody (608-907) (STJ117567)

简单介绍

Anti-FIG4 antibody (608-907) (STJ117567)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FIG4 (608-907) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:200-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FIG4
Gene ID:	9896
Uniprot ID:	FIG4_HUMAN
Immunogen Region:	608-907
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 608-907 of human FIG4 (NP_055660.1).
Immunogen Sequence:	WELPTDFYLHHKNTMRLLPT RRSYTYWWTPEVIKHLPLPY DEVICAVNLKKLIVKKFHKY EEEIDIHNEFFRPYELSSFD DTFCLAMTSSARDFMPKTVG IDPSPFTVRKPDETGKSVLG NKSNREEAVLQRKTAASAPP PPSEEAVSSSSEDDSGTDRE EEGSVSQRSTPVKMTDAGDS AKVTENVVQPMKELYGINLS DGLSEEDFSIYSRFVQLGQS QHKQDKNSQQPCSRCSDGV

Function	Dual specificity phosphatase component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Catalyzes the dephosphorylation of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) to form phosphatidylinositol 3-phosphate. Has serine-protein phosphatase activity acting on PIKfyve to stimulate its lipid kinase activity, its catalytically activity being required for maximal PI(3,5)P2 production. In vitro, hydrolyzes all three D5-phosphorylated polyphosphoinositide and although displaying preferences for PtdIns(3,5)P2, it is capable of hydrolyzing PtdIns(3,4,5)P3 and PtdIns(4,5)P2, at least in vitro.
Protein Name	Polyphosphoinositide Phosphatase Phosphatidylinositol 3 -5-Bisphosphate 5-Phosphatase Sac Domain-Containing Protein 3 Serine-Protein Phosphatase Fig4
Database Links	Reactome: R-HSA-1660514 Reactome: R-HSA-1660516 Reactome: R-HSA-1660517
Cellular Localisation	Endosome Membrane Localization Requires Vac14 And Pikfyve
Alternative Antibody Names	Anti-Polyphosphoinositide Phosphatase antibody Anti-Phosphatidylinositol 3 -5-Bisphosphate 5-Phosphatase antibody Anti-Sac Domain-Containing Protein 3 antibody Anti-Serine-Protein Phosphatase Fig4 antibody Anti-FIG4 antibody Anti-KIAA0274 antibody Anti-SAC3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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