Anti-FIS1 antibody (1-122) (STJ11104392) STJ11104392 上海玉博生物科技有限公司

Anti-FIS1 antibody (1-122) (STJ11104392)

简单介绍

Anti-FIS1 antibody (1-122) (STJ11104392)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Mitochondrial Fission 1 Protein (1-122) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:100-1:500
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FIS1
Gene ID:	51024
Uniprot ID:	FIS1_HUMAN
Immunogen Region:	1-122
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-122 of human TTC11/FIS1 (NP_057152.2).
Immunogen Sequence:	MEAVLNELVSVEDLLKFEKK FQSEKAAGSVSKSTQFEYAW CLVRSKYNDDIRKGIVLLEE LLPKGSKEEQRDYVFYLAVG NYRLKEYEKALKYVRGLLQT EPQNNQAKELERLIDKAMKK DG

Post Translational Modifications	Ubiquitinated by MARCHF5.
Function	Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event. Also mediates peroxisomal fission. May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis.
Protein Name	Mitochondrial Fission 1 Protein Fis1 Homolog Hfis1 Tetratricopeptide Repeat Protein 11 Tpr Repeat Protein 11
Database Links	Reactome: R-HSA-9603798
Cellular Localisation	Mitochondrion Outer Membrane Single-Pass Membrane Protein Peroxisome Membrane
Alternative Antibody Names	Anti-Mitochondrial Fission 1 Protein antibody Anti-Fis1 Homolog antibody Anti-Hfis1 antibody Anti-Tetratricopeptide Repeat Protein 11 antibody Anti-Tpr Repeat Protein 11 antibody Anti-FIS1 antibody Anti-TTC11 antibody Anti-CGI-135 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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