Anti-FKBP1A antibody (2-108) (STJ23667) STJ23667 上海玉博生物科技有限公司

Anti-FKBP1A antibody (2-108) (STJ23667)

简单介绍

Anti-FKBP1A antibody (2-108) (STJ23667)

产品描述

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FKBP1A (2-108) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FKBP1A
Gene ID:	2280
Uniprot ID:	FKB1A_HUMAN
Immunogen Region:	2-108
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 2-108 of FKBP12 (NP_000792.1).
Immunogen Sequence:	GVQVETISPGDGRTFPKRGQ TCVVHYTGMLEDGKKFDSSR DRNKPFKFMLGKQEVIRGWE EGVAQMSVGQRAKLTISPDY AYGATGHPGIIPPHATLVFD VELLKLE

Function	Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Protein Name	Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a Ppiase Fkbp1a 12 Kda Fk506-Binding Protein 12 Kda Fkbp Fkbp-12 Calstabin-1 Fk506-Binding Protein 1a Fkbp-1a Immunophilin Fkbp12 Rotamase
Database Links	Reactome: R-HSA-166208 Reactome: R-HSA-2025928 Reactome: R-HSA-2173789 Reactome: R-HSA-2173791 Reactome: R-HSA-3656535 Reactome: R-HSA-9679191 Reactome: R-HSA-9692916
Cellular Localisation	Cytoplasm Cytosol Sarcoplasmic Reticulum Membrane Peripheral Membrane Protein Cytoplasmic Side
Alternative Antibody Names	Anti-Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1a antibody Anti-Ppiase Fkbp1a antibody Anti-12 Kda Fk506-Binding Protein antibody Anti-12 Kda Fkbp antibody Anti-Fkbp-12 antibody Anti-Calstabin-1 antibody Anti-Fk506-Binding Protein 1a antibody Anti-Fkbp-1a antibody Anti-Immunophilin Fkbp12 antibody Anti-Rotamase antibody Anti-FKBP1A antibody Anti-FKBP1 antibody Anti-FKBP12 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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