Anti-FLRT2 antibody (300-400) (STJ119717) STJ119717 上海玉博生物科技有限公司

Anti-FLRT2 antibody (300-400) (STJ119717)

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产品名称：Anti-FLRT2 antibody (300-400) (STJ119717)
产品型号：STJ119717
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-FLRT2 antibody (300-400) (STJ119717)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FLRT2 (300-400) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FLRT2
Gene ID:	23768
Uniprot ID:	FLRT2_HUMAN
Immunogen Region:	300-400
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 300-400 of human FLRT2 (NP_037363.1).
Immunogen Sequence:	SNLKQLTARNNPWFCDCSIK WVTEWLKYIPSSLNVRGFMC QGPEQVRGMAVRELNMNLLS CPTTTPGLPLFTPAPSTASP TTQPPTLSIPNPSRSYTPPT P

Tissue Specificity	Expressed in pancreas, skeletal muscle, brain, and heart.
Post Translational Modifications	N-glycosylated. Proteolytic cleavage in the juxtamembrane region gives rise to a soluble ectodomain. Cleavage is probably effected by a metalloprotease.
Function	Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
Protein Name	Leucine-Rich Repeat Transmembrane Protein Flrt2 Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2
Database Links	Reactome: R-HSA-5654687
Cellular Localisation	Cell Membrane Single-Pass Membrane Protein Endoplasmic Reticulum Membrane Cell Junction Focal Adhesion Secreted Extracellular Space Extracellular Matrix Microsome Membrane Synapse Synaptosome Proteolytic Cleavage Gives Rise To A Shedded Ectodomain
Alternative Antibody Names	Anti-Leucine-Rich Repeat Transmembrane Protein Flrt2 antibody Anti-Fibronectin-Like Domain-Containing Leucine-Rich Transmembrane Protein 2 antibody Anti-FLRT2 antibody Anti-KIAA0405 antibody Anti-UNQ232 antibody Anti-PRO265 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-FLRT2 antibody (300-400) (STJ119717)