Anti-FMO3 antibody (300-400) [S5MR] (STJ11102955) STJ11102955 上海玉博生物科技有限公司

Anti-FMO3 antibody (300-400) [S5MR] (STJ11102955)

简单介绍

Anti-FMO3 antibody (300-400) [S5MR] (STJ11102955)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-FMO3 (300-400) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S5MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FMO3
Gene ID:	2328
Uniprot ID:	FMO3_HUMAN
Immunogen Region:	300-400
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 300-400 of human FMO3 (P31513).
Immunogen Sequence:	KPNVKEFTETSAIFEDGTIF EGIDCVIFATGYSFAYPFLD ESIIKSRNNEIILFKGVFPP LLEKSTIAVIGFVQSLGAAI PTVDLQSRWAAQVIKGTCTL P

Tissue Specificity	Liver.
Function	Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.
Protein Name	Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3 Dimethylaniline Oxidase 3 Fmo Ii Fmo Form 2 Hepatic Flavin-Containing Monooxygenase 3 Fmo 3 Trimethylamine Monooxygenase
Database Links	Reactome: R-HSA-217271 Reactome: R-HSA-5579019
Cellular Localisation	Microsome Membrane Single-Pass Membrane Protein Endoplasmic Reticulum Membrane
Alternative Antibody Names	Anti-Flavin-Containing Monooxygenase 3 antibody Anti-Dimethylaniline Monooxygenase N-Oxide-Forming 3 antibody Anti-Dimethylaniline Oxidase 3 antibody Anti-Fmo Ii antibody Anti-Fmo Form 2 antibody Anti-Hepatic Flavin-Containing Monooxygenase 3 antibody Anti-Fmo 3 antibody Anti-Trimethylamine Monooxygenase antibody Anti-FMO3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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