Anti-FNTA antibody (280-379) (STJ111424) STJ111424 上海玉博生物科技有限公司

Anti-FNTA antibody (280-379) (STJ111424)

简单介绍

Anti-FNTA antibody (280-379) (STJ111424)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FNTA (280-379) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FNTA
Gene ID:	2339
Uniprot ID:	FNTA_HUMAN
Immunogen Region:	280-379
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 280-379 of human FNTA (NP_002018.1).
Immunogen Sequence:	LKGILQDRGLSKYPNLLNQL LDLQPSHSSPYLIAFLVDIY EDMLENQCDNKEDILNKALE LCEILAKEKDTIRKEYWRYI GRSLQSKHSTENDSPTNVQQ

Post Translational Modifications	Phosphorylated. Phosphorylation is mediated by MUSK upon AGRIN stimulation and results in the activation of FNTA.
Function	Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Protein Name	Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha Caax Farnesyltransferase Subunit Alpha Ftase-Alpha Ras Proteins Prenyltransferase Subunit Alpha Type I Protein Geranyl-Geranyltransferase Subunit Alpha Ggtase-I-Alpha
Database Links	Reactome: R-HSA-111465 Reactome: R-HSA-2514859 Reactome: R-HSA-9648002 Reactome: R-HSA-9679191
Alternative Antibody Names	Anti-Protein Farnesyltransferase/Geranylgeranyltransferase Type-1 Subunit Alpha antibody Anti-Caax Farnesyltransferase Subunit Alpha antibody Anti-Ftase-Alpha antibody Anti-Ras Proteins Prenyltransferase Subunit Alpha antibody Anti-Type I Protein Geranyl-Geranyltransferase Subunit Alpha antibody Anti-Ggtase-I-Alpha antibody Anti-FNTA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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