Anti-FOLR1 antibody (41-90 aa) (STJ93159) STJ93159 上海玉博生物科技有限公司

Anti-FOLR1 antibody (41-90 aa) (STJ93159)

简单介绍

Anti-FOLR1 antibody (41-90 aa) (STJ93159)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Folate receptor alpha (41-90 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 ELISA 1:5000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FOLR1
Gene ID:	2348
Uniprot ID:	FOLR1_HUMAN
Immunogen Region:	41-90 aa
Specificity:	FR-Alpha Polyclonal Antibody detects endogenous levels of FR-Alpha protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human FOLR1 at the amino acid range 41-90

Post Translational Modifications	The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease.
Function	Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Protein Name	Folate Receptor Alpha Fr-Alpha Adult Folate-Binding Protein Fbp Folate Receptor 1 Folate Receptor - Adult Kb Cells Fbp Ovarian Tumor-Associated Antigen Mov18
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-5694530 Reactome: R-HSA-6807878
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Apical Cell Membrane Basolateral Cell Membrane Gpi-Like-Anchor Secreted Cytoplasmic Vesicle Clathrin-Coated Vesicle Endosome Endocytosed Into Cytoplasmic Vesicles And Then Recycled To The Cell Membrane
Alternative Antibody Names	Anti-Folate Receptor Alpha antibody Anti-Fr-Alpha antibody Anti-Adult Folate-Binding Protein antibody Anti-Fbp antibody Anti-Folate Receptor 1 antibody Anti-Folate Receptor - Adult antibody Anti-Kb Cells Fbp antibody Anti-Ovarian Tumor-Associated Antigen Mov18 antibody Anti-FOLR1 antibody Anti-FOLR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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