Anti-FPR2 antibody (130-210 aa) (STJ192622) STJ192622 上海玉博生物科技有限公司

Anti-FPR2 antibody (130-210 aa) (STJ192622)

简单介绍

Anti-FPR2 antibody (130-210 aa) (STJ192622)

产品描述

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Rat/Mouse/Swine
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-N-formyl peptide receptor 2 (130-210 aa) is suitable for use in Western Blot and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000 ELISA 1:5000-20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FPR2
Gene ID:	2358
Uniprot ID:	FPR2_HUMAN
Immunogen Region:	130-210 aa
Specificity:	FPR2 Polyclonal Antibody detects endogenous levels of protein.
Immunogen:	Synthesized peptide derived from the human protein at the amino acid range 130-210

Function	Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophil chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of pro-inflammatory signals such as LTB4 (leukotriene B4). Receptor for the chemokine-like protein FAM19A5, mediating FAM19A5-stimulated macrophage chemotaxis and the inhibitory effect on TNFSF11/RANKL-induced osteoclast differentiation. Acts as a receptor for humanin.
Protein Name	N-Formyl Peptide Receptor 2 Fmlp-Related Receptor I Fmlp-R-I Formyl Peptide Receptor-Like 1 Hm63 Lipoxin A4 Receptor Lxa4 Receptor Rfp
Database Links	Reactome: R-HSA-416476 Reactome: R-HSA-418594 Reactome: R-HSA-444473 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Associates With Amyloid-Beta Protein 42 Product Of App At The Cell Surface And The Complex Is Then Rapidly Internalized Also Internalized In The Presence Of Humanin
Alternative Antibody Names	Anti-N-Formyl Peptide Receptor 2 antibody Anti-Fmlp-Related Receptor I antibody Anti-Fmlp-R-I antibody Anti-Formyl Peptide Receptor-Like 1 antibody Anti-Hm63 antibody Anti-Lipoxin A4 Receptor antibody Anti-Lxa4 Receptor antibody Anti-Rfp antibody Anti-FPR2 antibody Anti-FPRH1 antibody Anti-FPRL1 antibody Anti-LXA4R antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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