Anti-FRK antibody (1-220) (STJ29694) STJ29694 上海玉博生物科技有限公司

Anti-FRK antibody (1-220) (STJ29694)

简单介绍

Anti-FRK antibody (1-220) (STJ29694)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FRK (1-220) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FRK
Gene ID:	2444
Uniprot ID:	FRK_HUMAN
Immunogen Region:	1-220
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FRK (NP_002022.1).
Immunogen Sequence:	MSNICQRLWEYLEPYLPCLS TEADKSTVIENPGALCSPQS QRHGHYFVALFDYQARTAED LSFRAGDKLQVLDTLHEGWW FARHLEKRRDGSSQQLQGYI PSNYVAEDRSLQAEPWFFGA IGRSDAEKQLLYSENKTGSF LIRESESQKGEFSLSVLDGA VVKHYRIKRLDEGGFFLTRR RIFSTLNEFVSHYTKTSDGL CVKLGKPCLKIQVPAPFDLS

Tissue Specificity	Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
Function	Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.
Protein Name	Tyrosine-Protein Kinase Frk Fyn-Related Kinase Nuclear Tyrosine Protein Kinase Rak Protein-Tyrosine Kinase 5
Database Links	Reactome: R-HSA-6798695 Reactome: R-HSA-8948751
Cellular Localisation	Cytoplasm Nucleus Predominantly Found In The Nucleus With A Small Fraction Found In The Cell Periphery
Alternative Antibody Names	Anti-Tyrosine-Protein Kinase Frk antibody Anti-Fyn-Related Kinase antibody Anti-Nuclear Tyrosine Protein Kinase Rak antibody Anti-Protein-Tyrosine Kinase 5 antibody Anti-FRK antibody Anti-PTK5 antibody Anti-RAK antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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