Anti-HSD17B3 antibody (1-310) (STJ110000) STJ110000 上海玉博生物科技有限公司

Anti-HSD17B3 antibody (1-310) (STJ110000)

简单介绍

Anti-HSD17B3 antibody (1-310) (STJ110000)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-HSD17B3 (1-310) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	HSD17B3
Gene ID:	3293
Uniprot ID:	DHB3_HUMAN
Immunogen Region:	1-310
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human HSD17B3 (NP_000188.1).
Immunogen Sequence:	MGDVLEQFFILTGLLVCLAC LAKCVRFSRCVLLNYWKVLP KSFLRSMGQWAVITGAGDGI GKAYSFELAKRGLNVVLISR TLEKLEAIATEIERTTGRSV KIIQADFTKDDIYEHIKEKL AGLEIGILVNNVGMLPNLLP SHFLNAPDEIQSLIHCNITS VVKMTQLILKHMESRQKGLI LNISSGIALFPWPLYSMYSA SKAFVCAFSKALQEEYKAKE VIIQVLTPYAVSTAMTKYL

Tissue Specificity	Testis.
Function	Catalyzes the conversion of 17-oxosteroids to 17beta-hydroxysteroids. Favors the reduction of androstenedione to testosterone. Testosterone is the key androgen driving male development and function. Uses NADPH while the two other EDH17B enzymes use NADH. Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at C-17. Can reduce 11-ketoandrostenedione as well as 11beta-hydroxyandrostenedione at C-17 to the respective testosterone forms.
Protein Name	17-Beta-Hydroxysteroid Dehydrogenase Type 3 17-Beta-Hsd 3 Estradiol 17-Beta-Dehydrogenase 2 Short Chain Dehydrogenase/Reductase Family 12c Member 2 Testicular 17-Beta-Hydroxysteroid Dehydrogenase Testosterone 17-Beta-Dehydrogenase 3
Database Links	Reactome: R-HSA-193048 Reactome: R-HSA-75876
Cellular Localisation	Endoplasmic Reticulum
Alternative Antibody Names	Anti-17-Beta-Hydroxysteroid Dehydrogenase Type 3 antibody Anti-17-Beta-Hsd 3 antibody Anti-Estradiol 17-Beta-Dehydrogenase 2 antibody Anti-Short Chain Dehydrogenase/Reductase Family 12c Member 2 antibody Anti-Testicular 17-Beta-Hydroxysteroid Dehydrogenase antibody Anti-Testosterone 17-Beta-Dehydrogenase 3 antibody Anti-HSD17B3 antibody Anti-EDH17B3 antibody Anti-SDR12C2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

产品留言

标题

联系人

联系电话

内容

验证码

点击换一张

注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!

产品目录