Anti-SLC4A2 antibody (200-300) (STJ110040) STJ110040 上海玉博生物科技有限公司

Anti-SLC4A2 antibody (200-300) (STJ110040)

简单介绍

Anti-SLC4A2 antibody (200-300) (STJ110040)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-SLC4A2 (200-300) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	SLC4A2
Gene ID:	6522
Uniprot ID:	B3A2_HUMAN
Immunogen Region:	200-300
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human SLC4A2 (NP_001186623.1).
Immunogen Sequence:	DDGGASGRPLPKAQPGHRSY NLQERRRIGSMTGAEQALLP RVPTDEIEAQTLATADLDLM KSHRFEDVPGVRRHLVRKNA KGSTQSGREGREPGPTPRAR P

Tissue Specificity	Isoform A: Expressed in the liver, stomach, kidney, prostate, thyroid and rectum. Isoform B1: Expressed in the liver and kidney. Isoform B2: Expressed in the liver and kidney.
Function	Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane. Plays an important role in osteoclast differentiation and function. Regulates bone resorption and calpain-dependent actin cytoskeleton organization in osteoclasts via anion exchange-dependent control of pH. Essential for intracellular pH regulation in CD8(+) T-cells upon CD3 stimulation, modulating CD8(+) T-cell responses.
Protein Name	Anion Exchange Protein 2 Ae 2 Anion Exchanger 2 Non-Erythroid Band 3-Like Protein Bnd3l Solute Carrier Family 4 Member 2
Database Links	Reactome: R-HSA-425381
Cellular Localisation	Isoform A: Apical Cell Membrane Multi-Pass Membrane Protein Basolateral Cell Membrane Isoform B1: Apical Cell Membrane Isoform B2: Apical Cell Membrane
Alternative Antibody Names	Anti-Anion Exchange Protein 2 antibody Anti-Ae 2 antibody Anti-Anion Exchanger 2 antibody Anti-Non-Erythroid Band 3-Like Protein antibody Anti-Bnd3l antibody Anti-Solute Carrier Family 4 Member 2 antibody Anti-SLC4A2 antibody Anti-AE2 antibody Anti-EPB3L1 antibody Anti-HKB3 antibody Anti-MPB3L antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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