Anti-TFAP2C antibody (350-450) (STJ110050) STJ110050 上海玉博生物科技有限公司

Anti-TFAP2C antibody (350-450) (STJ110050)

简单介绍

Anti-TFAP2C antibody (350-450) (STJ110050)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-TFAP2C (350-450) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	TFAP2C
Gene ID:	7022
Uniprot ID:	AP2C_HUMAN
Immunogen Region:	350-450
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human TFAP2C (NP_003213.1).
Immunogen Sequence:	NMLLAAQQLCKEFTELLSQD RTPHGTSRLAPVLETNIQNC LSHFSLITHGFGSQAICAAV SALQNYIKEALIVIDKSYMN PGDQSPADSNKTLEKMEKHR K

Post Translational Modifications	Sumoylated on Lys-10.which inhibits transcriptional activity.
Function	Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Protein Name	Transcription Factor Ap-2 Gamma Ap2-Gamma Activating Enhancer-Binding Protein 2 Gamma Transcription Factor Erf-1
Database Links	Reactome: R-HSA-3232118 Reactome: R-HSA-8866904 Reactome: R-HSA-8866906 Reactome: R-HSA-8866907 Reactome: R-HSA-8866910 Reactome: R-HSA-8866911 Reactome: R-HSA-9827857
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Transcription Factor Ap-2 Gamma antibody Anti-Ap2-Gamma antibody Anti-Activating Enhancer-Binding Protein 2 Gamma antibody Anti-Transcription Factor Erf-1 antibody Anti-TFAP2C antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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