Anti-PIP5K1B antibody (190-470) (STJ110060) STJ110060 上海玉博生物科技有限公司

Anti-PIP5K1B antibody (190-470) (STJ110060)

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产品名称：Anti-PIP5K1B antibody (190-470) (STJ110060)
产品型号：STJ110060
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-PIP5K1B antibody (190-470) (STJ110060)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-PIP5K1B (190-470) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	PIP5K1B
Gene ID:	8395
Uniprot ID:	PI51B_HUMAN
Immunogen Region:	190-470
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 190-470 of human PIP5K1B (NP_003549.1).
Immunogen Sequence:	NVLPRSMRMHFTYDLKGSTY KRRASRKEREKSNPTFKDLD FLQDMHEGLYFDTETYNALM KTLQRDCRVLESFKIMDYSL LLGIHFLDHSLKEKEEETPQ NVPDAKRTGMQKVLYSTAME SIQGPGKSGDGIITENPDTM GGIPAKSHRGEKLLLFMGII DILQSYRLMKKLEHSWKALV YDGDTVSVHRPSFYADRFLK FMNSRVFKKIQALKASPSKK RCNSIAALKATSQEIVSSI

Tissue Specificity	Detected in heart, pancreas, brain, kidney, skeletal muscle and lung.
Function	Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4)P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2), a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility. PtdIns(4,5)P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3), diacylglycerol (DAG) or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3/PIP3). Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of phospholipase PLD2. Together with PIP5K1A, is required, after stimulation by G-protein coupled receptors, for the synthesis of IP3 that will induce stable platelet adhesion.
Protein Name	Phosphatidylinositol 4-Phosphate 5-Kinase Type-1 Beta Pip5k1-Beta Ptdins(4p-5-Kinase 1 Beta Phosphatidylinositol 4-Phosphate 5-Kinase Type I Beta Pip5kibeta Protein Stm-7 Type I Phosphatidylinositol 4-Phosphate 5-Kinase Beta
Database Links	Reactome: R-HSA-1660499 Reactome: R-HSA-201688 Reactome: R-HSA-6811558
Cellular Localisation	Cytoplasm Cytosol Cell Membrane Endomembrane System Associated With Membranes
Alternative Antibody Names	Anti-Phosphatidylinositol 4-Phosphate 5-Kinase Type-1 Beta antibody Anti-Pip5k1-Beta antibody Anti-Ptdins(4p-5-Kinase 1 Beta antibody Anti-Phosphatidylinositol 4-Phosphate 5-Kinase Type I Beta antibody Anti-Pip5kibeta antibody Anti-Protein Stm-7 antibody Anti-Type I Phosphatidylinositol 4-Phosphate 5-Kinase Beta antibody Anti-PIP5K1B antibody Anti-STM7 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-PIP5K1B antibody (190-470) (STJ110060)