Anti-FSCN1 antibody (394-493) (STJ23712) STJ23712 上海玉博生物科技有限公司

Anti-FSCN1 antibody (394-493) (STJ23712)

简单介绍

Anti-FSCN1 antibody (394-493) (STJ23712)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FSCN1 (394-493) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FSCN1
Gene ID:	6624
Uniprot ID:	FSCN1_HUMAN
Immunogen Region:	394-493
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 394-493 of human Fascin/Fascin/FSCN1 (NP_003079.1).
Immunogen Sequence:	FIGCRKVTGTLDANRSSYDV FQLEFNDGAYNIKDSTGKYW TVGSDSAVTSSGDTPVDFFF EFCDYNKVAIKVGGRYLKGD HAGVLKASAETVDPASLWEY

Tissue Specificity	Ubiquitous.
Post Translational Modifications	Phosphorylation at Ser-39 inhibits actin-binding. Phosphorylation is required for the reorganization of the actin cytoskeleton in response to NGF.
Function	Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.
Protein Name	Fascin 55 Kda Actin-Bundling Protein Singed-Like Protein P55
Database Links	Reactome: R-HSA-6785807
Cellular Localisation	Cytoplasm Cytosol Cell Cortex Cytoskeleton Stress Fiber Cell Projection Filopodium Invadopodium Microvillus Cell Junction Colocalized With Rufy3 And F-Actin At Filipodia Of The Axonal Growth Cone Colocalized With Dbn1 And F-Actin At The Transitional Domain Of The Axonal Growth Cone
Alternative Antibody Names	Anti-Fascin antibody Anti-55 Kda Actin-Bundling Protein antibody Anti-Singed-Like Protein antibody Anti-P55 antibody Anti-FSCN1 antibody Anti-FAN1 antibody Anti-HSN antibody Anti-SNL antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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