Anti-DUSP1 antibody (318-367) (STJ94136) STJ94136 上海玉博生物科技有限公司

Anti-DUSP1 antibody (318-367) (STJ94136)

简单介绍

Anti-DUSP1 antibody (318-367) (STJ94136)

产品描述

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Rat/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Dual specificity protein phosphatase 1 (318-367) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DUSP1
Gene ID:	1843
Uniprot ID:	DUS1_HUMAN
Immunogen Region:	318-367
Specificity:	MKP-1 Polyclonal Antibody detects endogenous levels of MKP-1 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from human MKP1. AA range:318-367

Tissue Specificity	Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney.
Post Translational Modifications	Phosphorylation at Ser-359 and Ser-364 by MAPK1/ERK2 and MAPK3/ERK1 reduces its rate of degradation.
Function	Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.
Protein Name	Dual Specificity Protein Phosphatase 1 Dual Specificity Protein Phosphatase Hvh1 Mitogen-Activated Protein Kinase Phosphatase 1 Map Kinase Phosphatase 1 Mkp-1 Protein-Tyrosine Phosphatase Cl100
Database Links	Reactome: R-HSA-112409 Reactome: R-HSA-5675221
Cellular Localisation	Nucleus
Alternative Antibody Names	Anti-Dual Specificity Protein Phosphatase 1 antibody Anti-Dual Specificity Protein Phosphatase Hvh1 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 1 antibody Anti-Map Kinase Phosphatase 1 antibody Anti-Mkp-1 antibody Anti-Protein-Tyrosine Phosphatase Cl100 antibody Anti-DUSP1 antibody Anti-CL100 antibody Anti-MKP1 antibody Anti-PTPN10 antibody Anti-VH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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