Anti-ELL antibody (350-450) (STJ118877) STJ118877 上海玉博生物科技有限公司

Anti-ELL antibody (350-450) (STJ118877)

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产品名称：Anti-ELL antibody (350-450) (STJ118877)
产品型号：STJ118877
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-ELL antibody (350-450) (STJ118877)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-ELL (350-450) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ELL
Gene ID:	8178
Uniprot ID:	ELL_HUMAN
Immunogen Region:	350-450
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human ELL (NP_006523.1).
Immunogen Sequence:	PAVNGKLGVPNGREALLPTP GPPASTDTLSSSTHLPPRLE PPRAHDPLADVSNDLGHSGR DCEHGEAAAPAPTVRLGLPL LTDCAQPSRPHGSPSRSKPK K

Tissue Specificity	Expressed in all tissues tested. Highest levels found in placenta, skeletal muscle, testis and peripheral blood leukocytes.
Function	Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Elongation factor component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically required for stimulating the elongation step of RNA polymerase II- and III-dependent snRNA gene transcription. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.
Protein Name	Rna Polymerase Ii Elongation Factor Ell Eleven-Nineteen Lysine-Rich Leukemia Protein
Database Links	Reactome: R-HSA-112382 Reactome: R-HSA-167152 Reactome: R-HSA-167200 Reactome: R-HSA-167238 Reactome: R-HSA-167243 Reactome: R-HSA-167246 Reactome: R-HSA-167287 Reactome: R-HSA-167290 Reactome: R-HSA-674695 Reactome: R-HSA-6781827 Reactome: R-HSA-6796648 Reactome: R-HSA-6807505 Reactome: R-HSA-75955
Cellular Localisation	Nucleus Nucleus Speckle Cajal Body Colocalizes With Eaf2 To Nuclear Speckles Colocalizes With Coilin In Subnuclear Cajal And Histone Locus Bodies Translocates In The Lec Complex To Cajal And Histone Locus Bodies At Snrna Genes In A Ice1-Dependent Manner Associates To Transcriptionally Active Chromatin At Snrna Genes
Alternative Antibody Names	Anti-Rna Polymerase Ii Elongation Factor Ell antibody Anti-Eleven-Nineteen Lysine-Rich Leukemia Protein antibody Anti-ELL antibody Anti-C19orf17 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-ELL antibody (350-450) (STJ118877)