Anti-FABP5 antibody (1-135) (STJ11100060) STJ11100060 上海玉博生物科技有限公司

Anti-FABP5 antibody (1-135) (STJ11100060)

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产品名称：Anti-FABP5 antibody (1-135) (STJ11100060)
产品型号：STJ11100060
产品展商：ST john's laboratory
产品文档：无相关文档

简单介绍

Anti-FABP5 antibody (1-135) (STJ11100060)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FABP5 (1-135) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FABP5
Gene ID:	2171
Uniprot ID:	FABP5_HUMAN
Immunogen Region:	1-135
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human FABP5 (NP_001435.1).
Immunogen Sequence:	MATVQQLEGRWRLVDSKGFD EYMKELGVGIALRKMGAMAK PDCIITCDGKNLTIKTESTL KTTQFSCTLGEKFEETTADG RKTQTVCNFTDGALVQHQEW DGKESTITRKLKDGKLVVEC VMNNVTCTRIYEKVE

Tissue Specificity	Keratinocytes.highly expressed in psoriatic skin. Expressed in brain gray matter.
Function	Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta.which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation. May be involved in keratinocyte differentiation.
Protein Name	Fatty Acid-Binding Protein 5 Epidermal-Type Fatty Acid-Binding Protein E-Fabp Fatty Acid-Binding Protein - Epidermal Psoriasis-Associated Fatty Acid-Binding Protein Homolog Pa-Fabp
Database Links	Reactome: R-HSA-163560 Reactome: R-HSA-5362517 Reactome: R-HSA-6798695
Cellular Localisation	Cytoplasm Nucleus Synapse Postsynaptic Density Secreted Localizes Primarily To The Cytoplasm Upon Certain Ligand Binding A Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into Nucleus Secreted By Astrocytes But Not By Neurons
Alternative Antibody Names	Anti-Fatty Acid-Binding Protein 5 antibody Anti-Epidermal-Type Fatty Acid-Binding Protein antibody Anti-E-Fabp antibody Anti-Fatty Acid-Binding Protein - Epidermal antibody Anti-Psoriasis-Associated Fatty Acid-Binding Protein Homolog antibody Anti-Pa-Fabp antibody Anti-FABP5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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Anti-FABP5 antibody (1-135) (STJ11100060)