Anti-FBP1 antibody (239-338) [S2MR] (STJ11101382) STJ11101382 上海玉博生物科技有限公司

Anti-FBP1 antibody (239-338) [S2MR] (STJ11101382)

简单介绍

Anti-FBP1 antibody (239-338) [S2MR] (STJ11101382)

产品描述

Host:	Rabbit
Applications:	WB/IF
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-FBP1 (239-338) is suitable for use in Western Blot and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S2MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FBP1
Gene ID:	2203
Uniprot ID:	F16P1_HUMAN
Immunogen Region:	239-338
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 239-338 of human FBP1 (P09467).
Immunogen Sequence:	APYGARYVGSMVADVHRTLV YGGIFLYPANKKSPNGKLRL LYECNPMAYVMEKAGGMATT GKEAVLDVIPTDIHQRAPVI LGSPDDVLEFLKVYEKHSAQ

Tissue Specificity	Expressed in pancreatic islets.
Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity.increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Protein Name	Fructose-1 -6-Bisphosphatase 1 Fbpase 1 D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 Liver Fbpase
Database Links	Reactome: R-HSA-70263
Alternative Antibody Names	Anti-Fructose-1 -6-Bisphosphatase 1 antibody Anti-Fbpase 1 antibody Anti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 1 antibody Anti-Liver Fbpase antibody Anti-FBP1 antibody Anti-FBP antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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