Anti-FCN1 antibody (30-326) (STJ28670) STJ28670 上海玉博生物科技有限公司

Anti-FCN1 antibody (30-326) (STJ28670)

简单介绍

Anti-FCN1 antibody (30-326) (STJ28670)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FCN1 (30-326) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FCN1
Gene ID:	2219
Uniprot ID:	FCN1_HUMAN
Immunogen Region:	30-326
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-326 of human FCN1 (NP_001994.2).
Immunogen Sequence:	ADTCPEVKVVGLEGSDKLTI LRGCPGLPGAPGPKGEAGVI GERGERGLPGAPGKAGPVGP KGDRGEKGMRGEKGDAGQSQ SCATGPRNCKDLLDRGYFLS GWHTIYLPDCRPLTVLCDMD TDGGGWTVFQRRMDGSVDFY RDWAAYKQGFGSQLGEFWLG NDNIHALTAQGSSELRVDLV DFEGNHQFAKYKSFKVADEA EKYKLVLGAFVGGSAGNSLT GHNNNFFSTKDQDNDVSSS

Tissue Specificity	Peripheral blood leukocytes, monocytes and granulocytes. Also detected in spleen, lung, and thymus, may be due to the presence of tissue macrophages or trapped blood in these tissues. Not detected on lymphocytes.
Function	Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8. Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Protein Name	Ficolin-1 Collagen/Fibrinogen Domain-Containing Protein 1 Ficolin-A Ficolin-Alpha M-Ficolin
Database Links	Reactome: R-HSA-166662 Reactome: R-HSA-166663 Reactome: R-HSA-2855086 Reactome: R-HSA-6798695
Cellular Localisation	Secreted Cell Membrane Peripheral Membrane Protein Extracellular Side Found On The Monocyte And Granulocyte Surface
Alternative Antibody Names	Anti-Ficolin-1 antibody Anti-Collagen/Fibrinogen Domain-Containing Protein 1 antibody Anti-Ficolin-A antibody Anti-Ficolin-Alpha antibody Anti-M-Ficolin antibody Anti-FCN1 antibody Anti-FCNM antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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