Anti-FDFT1 antibody (11-61 aa) (STJ195085) STJ195085 上海玉博生物科技有限公司

Anti-FDFT1 antibody (11-61 aa) (STJ195085)

简单介绍

Anti-FDFT1 antibody (11-61 aa) (STJ195085)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Squalene synthase (11-61 aa) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FDFT1
Gene ID:	2222
Uniprot ID:	FDFT_HUMAN
Immunogen Region:	11-61 aa
Specificity:	This antibody detects endogenous levels of FDFT at Human/Mouse/Rat
Immunogen:	Synthesized peptide derived from the human FDFT at the amino acid range 11-61

Function	Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway.
Protein Name	Squalene Synthase Sqs Ss Fpp -Fpp Farnesyltransferase Farnesyl-Diphosphate Farnesyltransferase Farnesyl-Diphosphate Farnesyltransferase 1
Database Links	Reactome: R-HSA-191273 Reactome: R-HSA-1989781 Reactome: R-HSA-2426168
Cellular Localisation	Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein
Alternative Antibody Names	Anti-Squalene Synthase antibody Anti-Sqs antibody Anti-Ss antibody Anti-Fpp -Fpp Farnesyltransferase antibody Anti-Farnesyl-Diphosphate Farnesyltransferase antibody Anti-Farnesyl-Diphosphate Farnesyltransferase 1 antibody Anti-FDFT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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