Anti-FGF13 antibody (1-245) (STJ110204) STJ110204 上海玉博生物科技有限公司

Anti-FGF13 antibody (1-245) (STJ110204)

简单介绍

Anti-FGF13 antibody (1-245) (STJ110204)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FGF13 (1-245) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FGF13
Gene ID:	2258
Uniprot ID:	FGF13_HUMAN
Immunogen Region:	1-245
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human FGF13 (NP_004105.1).
Immunogen Sequence:	MAAAIASSLIRQKRQARERE KSNACKCVSSPSKGKTSCDK NKLNVFSRVKLFGSKKRRRR RPEPQLKGIVTKLYSRQGYH LQLQADGTIDGTKDEDSTYT LFNLIPVGLRVVAIQGVQTK LYLAMNSEGYLYTSELFTPE CKFKESVFENYYVTYSSMIY RQQQSGRGWYLGLNKEGEIM KGNHVKKNKPAAHFLPKPLK VAMYKEPSLHDLTEFSRSGS GTPTKSRSVSGVLNGGKSM

Tissue Specificity	Ubiquitously expressed. Predominantly expressed in the nervous system.
Post Translational Modifications	May be phosphorylated.
Function	Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons.
Protein Name	Fibroblast Growth Factor 13 Fgf-13 Fibroblast Growth Factor Homologous Factor 2 Fhf-2
Database Links	Reactome: R-HSA-5576892
Cellular Localisation	Isoform 1: Nucleus Isoform 2: Cytoplasm Nucleus Isoform 3: Cytoplasm Isoform 4: Cytoplasm Isoform 5: Cytoplasm Cell Projection Filopodium Growth Cone Dendrite Cell Membrane Sarcolemma Cytoplasm Not Secreted Localizes To The Lateral Membrane And Intercalated Disks Of Myocytes
Alternative Antibody Names	Anti-Fibroblast Growth Factor 13 antibody Anti-Fgf-13 antibody Anti-Fibroblast Growth Factor Homologous Factor 2 antibody Anti-Fhf-2 antibody Anti-FGF13 antibody Anti-FHF2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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