Anti-FLOT2 antibody (239-428) (STJ11104327) STJ11104327 上海玉博生物科技有限公司

Anti-FLOT2 antibody (239-428) (STJ11104327)

简单介绍

Anti-FLOT2 antibody (239-428) (STJ11104327)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Flotillin-2 (239-428) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:1000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FLOT2
Gene ID:	2319
Uniprot ID:	FLOT2_HUMAN
Immunogen Region:	239-428
Immunogen:	Recombinant Protein corresponding to a sequence within amino acids 239-428 of human FLOT2 (NP_004466.2).
Immunogen Sequence:	LAYELQGAREQQKIRQEEIE IEVVQRKKQIAVEAQEILRT DKELIATVRRPAEAEAHRIQ QIAEGEKVKQVLLAQAEAEK IRKIGEAEAAVIEAMGKAEA ERMKLKAEAYQKYGDAAKMA LVLEALPQIAAKIAAPLTKV DEIVVLSGDNSKVTSEVNRL LAELPASVHALTGVDLSKIP LIKKATGVQV

Tissue Specificity	In skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
Post Translational Modifications	ZDHHC5-catalyzed palmitoylation predominantly occurs at Cys-4. ZDHHC5-catalyzed palmitoylation may be required for the formation of higher-order complexes and for neurite outgrowth in cultured neural stem cells.
Function	May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
Protein Name	Flotillin-2 Epidermal Surface Antigen Esa Membrane Component Chromosome 17 Surface Marker 1
Database Links	Reactome: R-HSA-5213460 Reactome: R-HSA-5675482 Reactome: R-HSA-8849932 Reactome: R-HSA-8980692 Reactome: R-HSA-9013026 Reactome: R-HSA-9013106 Reactome: R-HSA-9696264 Reactome: R-HSA-9696273
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Membrane Caveola Endosome Lipid-Anchor Membrane-Associated Protein Of Caveolae
Alternative Antibody Names	Anti-Flotillin-2 antibody Anti-Epidermal Surface Antigen antibody Anti-Esa antibody Anti-Membrane Component Chromosome 17 Surface Marker 1 antibody Anti-FLOT2 antibody Anti-ESA1 antibody Anti-M17S1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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