Anti-SCN2B antibody (30-160) (STJ110034) STJ110034 上海玉博生物科技有限公司

Anti-SCN2B antibody (30-160) (STJ110034)

简单介绍

Anti-SCN2B antibody (30-160) (STJ110034)

产品描述

Host:	Rabbit
Applications:	WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-SCN2B (30-160) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	SCN2B
Gene ID:	6327
Uniprot ID:	SCN2B_HUMAN
Immunogen Region:	30-160
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-160 of human SCN2B (NP_004579.1).
Immunogen Sequence:	MEVTVPATLNVLNGSDARLP CTFNSCYTVNHKQFSLNWTY QECNNCSEEMFLQFRMKIIN LKLERFQDRVEFSGNPSKYD VSVMLRNVQPEDEGIYNCYI MNPPDRHRGHGKIHLQVLME EPPERDSTVAV

Tissue Specificity	Brain specific.
Function	Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
Protein Name	Sodium Channel Subunit Beta-2
Database Links	Reactome: R-HSA-445095 Reactome: R-HSA-5576892 Reactome: R-HSA-9717207
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Sodium Channel Subunit Beta-2 antibody Anti-SCN2B antibody Anti-UNQ326 antibody Anti-PRO386 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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