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Anti-SULT2B1 antibody (1-365) (STJ110047)

Anti-SULT2B1 antibody (1-365) (STJ110047)
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  • 产品名称:Anti-SULT2B1 antibody (1-365) (STJ110047)
  • 产品型号:STJ110047
  • 产品展商:ST john's laboratory
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简单介绍
Anti-SULT2B1 antibody (1-365) (STJ110047)
产品描述
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SULT2B1 (1-365) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SULT2B1
Gene ID: 6820
Uniprot ID: ST2B1_HUMAN
Immunogen Region: 1-365
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human SULT2B1 (NP_814444.1).
Immunogen Sequence: MDGPAEPQIPGLWDTYEDDI SEISQKLPGEYFRYKGVPFP VGLYSLESISLAENTQDVRD DDIFIITYPKSGTTWMIEII CLILKEGDPSWIRSVPIWER APWCETIVGAFSLPDQYSPR LMSSHLPIQIFTKAFFSSKA KVIYMGRNPRDVVVSLYHYS KIAGQLKDPGTPDQFLRDFL KGEVQFGSWFDHIKGWLRMK GKDNFLFITYEELQQDLQGS VERICGFLGRPLGKEALGS
Tissue Specificity Expressed in the stratum granulosum-stratum corneum junction in the skin (at protein level). Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung.
Post Translational Modifications Phosphorylated.
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation. Responsible for the sulfation of cholesterol. Catalyzes sulfation of the 3beta-hydroxyl groups of steroids, such as, pregnenolone and dehydroepiandrosterone (DHEA). Preferentially sulfonates cholesterol, while it has also significant activity with pregnenolone and DHEA. Plays a role in epidermal cholesterol metabolism and in the regulation of epidermal proliferation and differentiation. Isoform 2: Sulfonates pregnenolone but not cholesterol.
Protein Name Sulfotransferase 2b1
Alcohol Sulfotransferase
Hydroxysteroid Sulfotransferase 2
Sulfotransferase Family 2b Member 1
Sulfotransferase Family Cytosolic 2b Member 1
St2b1
Database Links Reactome: R-HSA-156584
Cellular Localisation Cytoplasm
Cytosol
Microsome
Nucleus
Phosphorylation Of Ser-348 Is Required For Translocation To The Nucleus
Alternative Antibody Names Anti-Sulfotransferase 2b1 antibody
Anti-Alcohol Sulfotransferase antibody
Anti-Hydroxysteroid Sulfotransferase 2 antibody
Anti-Sulfotransferase Family 2b Member 1 antibody
Anti-Sulfotransferase Family Cytosolic 2b Member 1 antibody
Anti-St2b1 antibody
Anti-SULT2B1 antibody
Anti-HSST2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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