产品详情
简单介绍：
Anti-D-dimer (human, dog)
详情介绍：
- Cat. No.
- ABS 015-28
- Product name
- Anti-D-dimer (human, dog)
- Description
-
Mouse monoclonal antibody
- Specificity
ABS 015-28 binds human D-dimer. Cross-reacts with directly coated D-monomer but not with directly coated fibrinogen.
- Immunogen
Purified human D-dimer
- Application
- ELISA, WB
- Species reactivity (positive)
- Human, dog
- Species reactivity (negative)
- Not determined
- Subclass
IgG1/k
- Gene ID
- 2243, 475473
- Clone number
- 28
- Epitope
When tested in a pair with itself, with ABS 015-22 and a fibrinogen-specific polyclonal antibody, the epitope appears to relate to the neo-epitope formed by cleavage of D-dimer from fibrin.
- Content
Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
- Purification
- Protein-A purified
- Form
- Liquid
- Solvent
- 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
- Storage
- 4-8ºC without exposure to light. No precautions necessary during handling.
- Target
D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis.
- Application 1
- ELISA
ABS 015-028 binds free D-dimer in solution.ABS 015-028 works as capture antibody in sandwich ELISA with biotinylated ABS 015-28 or ABS 015-22 as detection antibody.Biotinylated ABS 015-028 works as detection antibody in sandwich ELISA with ABS 015-22 or ABS 015-28 as capture antibody.The combination with ABS 015-28 as capture antibody and ABS 015-22B as detection antibody is recommended.
The calibration curve of a sandwich assay for D-Dimer using ABS 015-28 as capture antibody and ABS 015-22B as the biotinylated detection antibody. - Application 2
WB
Due to reducing conditions in Western blotting ABS 015-28 binds the beta-chain (40kDa) of D-Dimer, and not the entire D-Dimer complex.
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