For Research Use Only. Not for use in diagnostic procedures.
Purified human complement component C6 Complement component C6 is unique to the terminal complement pathway. It is a single chain protein with a molecular weight of 120 KDA and is present in plasma at approximately 60 mg/L. Together with the other proteins of the terminal pathway, C6 constitutes the membrane attack complex or MAC.
All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.
Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.
References
Nicholson-Weller, Butko, P, Wessels, M. Role of Complement Component C1q in IgG independent Opsonophagocytosis of Group B Streptococus, J. Immunol 163:2761-2768, 1999.
Barbashov, S., Wang C., Nicholson-Weller, A. Serum amyloid P component forms a stable complex with human C5b-6, J. Immunol 158:3830-3835, 1997.
Koski, C., Dashell, S. Sublytic terminal complement complex decreases Po gene expression in schwan cells, J Neurochem 73(6):2321-2330, 1999.
Features & Benefits
| Feature | Benefit |
|---|
Product Specifications
| Product Spec Name | Product Spec Data |
|---|---|
|
Concentration
|
1.0 mg/mL |
|
Volume/vial
|
250 μL/vial |
|
Storage
|
At or below –70oC |
|
Purity
|
> 85% |
|
Buffer
|
PBS |
Ordering Information
| Catalog Number | Kit Size / Case Size |
|---|---|
|
A404
|
250 μL/vial
|
