产品详情
简单介绍：
BAZ2-ICR,BAZ2BromodomainInhibitor
详情介绍：
Product Information
| Molecular Weight: | 357.41 |
| Formula: | C20H19N7 |
| Purity: | ≥98% |
| CAS#: | n/a |
| Solubility: | DMSO up to 100 mM |
| Chemical Name: | 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile |
| Storage: | Powder: 4oC 1 year. DMSO: 4oC 3 month; -20oC 1 year. |
Biological Activity:
BAZ2-ICR is a potent and selective BAZ2 bromodomain inhibitor with Kd values of 109 and 170 nM for BAZ2A and BAZ2B, respectively. It exhibits 15-fold selectivity for the BAZ2 bromodomain over the CERC2 bromodomain and >100-fold selectivity over a range of other bromodomains. It shows accelerated FRAP recovery at 1 µM in the BAZ2A FRAP assay.
How to Use:
In vitro: BAZ2-ICR was used at 1-10 µM final concentration in various in vitro assays.
In vivo: n/a
Reference:
- 1. http://www.thesgc.org/chemical-probe/BAZ2-ICR
Products are for research use only. Not for human use.
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