企业信息
17
  • 入驻时间: 2008-08-20
  • 联系人:客户经理
  • 电话:400-968-7988
  • 联系时,请说明易展网看到的
  • Email:fuwu@bioleaf.com
产品详情
  • 产品名称:IDH2-C100,IHD2Inhibitor

  • 产品型号:M60190-2s
  • 产品厂商:其它品牌
  • 产品价格:129
  • 折扣价格:0
  • 产品文档:
你添加了1件商品 查看购物车
简单介绍:
IDH2-C100,IHD2Inhibitor
详情介绍:
Product Information
Molecular Weight: 305.38
Formula: C18H19N5
Purity: ≥98%
CAS#: n/a
Solubility: DMSO up to 50 mM
Chemical Name: N2-isopropyl-N4,6-diphenyl-1,3,5-triazine-2,4-diamine
Storage: Powder: 4oC 1 year. DMSO: 4oC 3 month; -20oC 1 year.

Biological Activity: 

IDH2-C100 is a potent and selective inhibitor of IDH2 R140Q and R172K mutant first reported in patent WO 2013102431. It can inhibit the enzymatic activity of IDH2 R140Q and R172K in vitro with an IC50 < 0.1 µM. It has IC50 < 0.1 µM in U87MG pLVX-IDH2 R140Q-neo cell based assay. It is an analog of clinical IDH2 inhibitor AG-221 by Thomson Reuters Integrity analysis.

 

How to Use:

  • In vitro: IDH2-C100 was used at 1-5 µM in vitro and cellular assays.
  • In vivo: n/a

 

Reference:

  • 1. Giovanni Cianchetta, et al. Therapeutically active compounds and their methods of use. (2013) PCT WO 2013102431

 
 

 

Products are for research use only. Not for human use.

标题:
内容:
联系人:
联系电话:
Email:
公司名称:
联系地址:
 
 
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
相关文章

沪公网安备 31011202007337号