H3K79me3 Mouse Monoclonal Antibody
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Clonality: Mouse IG1 |
Source: Mouse |
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Applications: WB: 1:500-1:2000 |
Cross-Reactivity: HMRat |
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Concentration: 100 ug/100 ul |
Detected band (by western) MW: 15 KD |
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Alt. Names
H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody
Specificity:
The Histone H3 (tri methyl K79) mouse monoclonal antibody can recognize endogenous Histone H3 (tri methyl K79) proteins.
Immunogen:
Mouse monoclonal antibody is prepared by immunizing synthetic peptide coupled to KLH.
Storage Condition and Buffer:
Store at -20°C. Stable for one year from the date of shipment. 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol
H3K79 methylation is one of the gene activation markers. DOT1L methyltransferase usually involves in H3K79 methylation, playing essential roles in embryonic development, hematopoiesis, cardiac function and the development of leukemia.
To detect marker H3K79 methylation status, pick from our H3K79 polyclonal antibody series or H3K79 mouse monoclonal antibody series.
References:
1. Robert A Copeland. Protein methyltransferases in cancer. (2013) AACR Annual Meeting.
2. Roy M Pollock. Preclinical Characterization of a Potent, Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL-Rearranged Leukemia. (2012) 54th ASH Annual Meeting and Exposition.
Product is for research use only. Not for human use.
