产品详情
简单介绍：
Bafilomycin A1
详情介绍：
- Description
- Data Sheet
Highly potent, selective inhibitor of vacuolar type H+-ATPase (V-ATPase). Selective for V-ATPase over other ATP hydrolyzing enzymes such as F-ATPases and the H+/K+-ATPase (P-ATPase). Lysosomal proton pump inhibitor. Autophagy inhibitor - either by blocking autophagosome-lysosome fusion or by blocking lysosomal degradation.
| Chemical name | (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one |
| CAS number | 88899-55-2 |
| Molecular weight | 622.8 |
| Formula | C35H58O9 |
| Solubility | DMSO, ethanol and methanol, all up to 5mg/ml |
| Purity | >98% |
| Storage | -20°C |
| Datasheet | A010-502
 |
| Regulatory statement | Product for research use only. Not intended for diagnostic or therapeutic use. |
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