产品详情
简单介绍:
Rapamycin
详情介绍:
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- Description
- Data Sheet
A macrocyclic triene antibiotic that binds to and inhibits the molecular target of rapamycin (mTOR) in complex with FKBP12. mTor acts as a negative regulator of autophagy hence inhibiton with rapamycin leads to activation of autophagy. Rapamycin is a potent immunosuppressant and has anticancer and antifungal activity. In addition it inhibits interleukin-2-induced phosphorylation and activation of p70 S6 kinase.
Chemical name | 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine |
CAS number | 53123-88-9 |
Molecular weight | 914.2 |
Formula | C51H79NO13 |
Solubility | Soluble in chloroform, DMSO, methanol or ethanol |
Purity | ≥98% |
Storage | -20°C |
Datasheet | A010-501
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Regulatory statement | Product for research use only. Not intended for diagnostic or therapeutic use. |
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