别名： 四甲基-5-(1H-1,2,4-三唑-1-基甲基)-1,3-苯二乙腈 英文名：Anastrozole 分子式：C17H19N5 分子量： 293.37 外观： White crystalline powder 溶解性： slightly soluble in 0.1mol/L hydrochloric acid, water solution,freely soluble in methanol,ethanol, chloroform and ethyl acetate. 纯度： >99% CAS No： 120511-73-1 Biological Activity: Anastrozole inhibits the enzyme aromatase, which is responsible for converting androgens to estrogens. Anastrozole binds reversibly to the aromatase enzyme through competitive inhibition. Elevated levels of estrogens may increase the severity of breast cancer, as sex hormones can cause hyperplasia and differentiation at estrogen receptor sites. Anastrozole is used to treat breast cancer after surgery and for metastases in post-menopausal women.