别名：N-(3-乙炔苯基)-[6,7-二(2-甲氧基乙氧基)]喹唑啉-4-胺盐酸盐 化学名称：[6,7-Bis-(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)-amine hydrochloride 英文名：Erlotinib hydrochloride 分子式：C22H23N3O4.HCl 分子量：429.90 纯度： >99% 外观：Off- white to white crystalline powder CAS No：183319-69-9
Biological Activity:
EGFR inhibitor; Erlotinib inhibits EGFR tyrosine kinase autophosphorylation by inhibition of the intracellular domain. Studies in cell lines and enzyme assays have both shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl.