[
A 769662
]
Product Name:
A 769662
Product Model:
C13240
Manufacturer:
A
file:
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Product Description
A 769662#844499-71-4#C20H12N2O3S#360.39#Soluble in DMSO, slightly Soluble in ethanol#Off-white powder#>99%#500mg,1g,2g#Desiccate at -20°C#Potent, reversible AMP-activated protein kinase (AMPK) activator.
A 769662
Chemical name: 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile
Biological Activity
Potent, reversible AMP-activated protein kinase (AMPK) activator (EC50 = 0.8 μM) that displays selectivity towards β1 subunit-containing heterotrimers. Inhibits fatty acid synthesis (IC50 = 3.2 μM) and decreases plasma glucose and triglyceride levels in vivo.