[
(+)-Bicuculline
]
Product Name:
(+)-Bicuculline
Product Model:
C10599
Manufacturer:
B
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Product Description
(+)-Bicuculline,d-Bicuculline#485-49-4#C20H17NO6#367.36#soluble in benzene,chloroform,ethyl
acetate. Sparingly soluble in alcohol and ether#Pale yellow crystalline powder#>99%#1g,2g,5g#Store at -2#(+)-Bicuculline is an antagonist of the GABAA receptor.
(+)-Bicuculline
Chemical Name:(6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-Methyl-1,3-Dioxolo[4,5-G]Lisoquinolin-5-Yl]Furo[3,4-E]-1,3-Benzodioxol-8(6H)-One; (+)-Bicuculline; D-Bicuculline; Nsc 32192;
Biological Activity:
(+)-Bicuculline is an antagonist of the GABAA receptor. (+)-Bicuculline is the parent compound of the water soluble N-methyl derivatives (-)-Bicuculline methiodide and (-)-Bicuculline methobromide. Antagonism of the GABAA receptor by (+)-Bicuculline blocks the neurotransmission inhibition function of the GABA system, utilized to induce an artificial epileptic state in laboratory studies
(+)-Bicuculline
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