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订购货号 | 产品名称及规格 | 价格(¥) |
21860 | TFA-Amino modifier CPG 500, 250 mg | 1560.00 |
41860 | TFA-Amino modifier CPG 500, 1 g | 4940.00 |
51860 | TFA-Amino modifier CPG 500, 5 g | 21450.00 |
This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.
The reagent is based on hydroxyprolinol core - a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.
General properties
Appearance: |
off-white beads |
Quality control: |
NMR 1H and HPLC (95%) of bound reagent, loading measurement |
Storage conditions: |
Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate. |
CPG details
Pore size, Å: |
500 |
Typical loading, umol/g: |
70−90 |
Coupling conditions: |
standard coupling, identical to normal nucleobases |
Cleavage conditions: |
ammonia, 2 h at room temperature |
Deprotection conditions: |
identical to protected nucleobases |