产品详情
简单介绍：
mKLF4 Adenovirus (Mouse)
详情介绍：
| Print Version | |
| Vector | pAdeno |
| Promoter | CMV |
| Insert | mKLF4 |
| Picture |  |
| Organism | Mouse |
| Accession # | Q60793 |
| Alias | Ezf, Gklf, Zie |
| Protein Type | Wild Type |
| Protein Family | Belongs to the krueppel C2H2-type zinc-finger protein family. |
| Functions | Transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. This product can be used in combination with other iPSC factor for the induction of iPSC reprogramming. |
| Cell Types | Highest expression in the colon. Lower levels in testis, lung and small intestine. |
| Protein Location | Nucleus |
| Gene Type | cDNA |
| Purification | By Ion-Exchange column. |
| Quality Control | By sequencing and Western blot analysis of transgene expression in transduced cells. Functional test includes iPSC reprogramming. |
| Titer | >1x106pfu/mL |
| Storage | 10 mM Tris-HCl, pH 8.0 |
| Shipping | High titer adenoviruses are shipped with dry ice and low titer adenoviruses are shipped with ice packs. For long term storage, it is recommended to store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles. |
| Notes | For Research Use Only, not for therapeutic or diagnostic purposes. |
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