[
Torin 1
]
Product Name:
Torin 1
Product Model:
C14284
Manufacturer:
T
file:
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Product Description
Torin 1#1222998-36-8#C35H28F3N5O2#607.62#Soluble to 1 mM in DMSO#Grey solid#>99%#500mg,1g,2g,5g#Store at +4°C#Potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2).
Torin 1
Chemical Name: 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one
Biological Activity
Potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34.