[
Torin 2
]
Product Name:
Torin 2
Product Model:
C14285
Manufacturer:
T
file:
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Product Description
Torin 2#1223001-51-1#C24H15F3N4O#432.4#Soluble to 20 mM in DMSO#Yellow solid#>98%#500mg,1g,2g,5g#Store at +4°C#Potent and selective mTOR inhibitor (IC50 = 2.1 nM).
Torin 2
Chemical Name: 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)-one
Biological Activity
Potent and selective mTOR inhibitor (IC50 = 2.1 nM). Displays 800-fold cellular selectivity for mTOR over PI3K (cellular EC50 values are 0.25 and 200 nM for mTOR and PI3K respectively). Orally available