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AZD1152-HQPA(Barasertib)
]
Product Name:
AZD1152-HQPA(Barasertib)
Product Model:
C13349
Manufacturer:
A
file:
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Product Description
Barasertib, AZD1152#722544-51
6#C26H30FN7O3#507.56#DMSO#Crystalline solid#>99%#100mg,200mg,500mg,1g,2g#at -20℃ 2 years# A potent and specific Aurora kinase B inhibitor
AZD1152-HQPA(Barasertib)
Chemical Name:
2-(5-((7-3-(Ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-3-yl)-N-(3-fluorophenyl)acetamide
Biological Activity:
A potent and specific Aurora kinase B inhibitor. It is 1000-fold more selective for aurora kinase B than for aurora kinase A ( Ki values of 1300 nM and 0.36 nM for aurora kinase A and B, respectively). At concentrations as low as 0.01 µM, AZD 1152 produced a significant (p<0.05) decrease in the ability of NB4 cells to proliferate by 48 hours
AZD1152-HQPA(Barasertib)
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