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Pharmacology
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Angiogenesis/Tyrosine Kinase
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EGFR(HER)/VEGFR-PDGFR
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Brivanib alaninate(BMS-582664)
C13404
BMS-582664#649735-63-7#C22H24FN5O4#441.46#N/A#White solid#>99%##at -20 degree celsius 2 years#A novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor.
WZ4002
C14347
WZ-4002#213269-23-8#C25H27ClN6O3#494.18#Soluble in DMSO to 35 mM# #>99%#500mg,1g,2g,5g#at -20℃#WZ4002 is an EGFR T790M inhibitor(IC50<20nM).
AP24534(Ponatinib)
C14041
Ponatinib#943319-70-8#C29H27F3N6O#532.56#Soluble to 100 mM in DMSO and to 50 mM in ethanol#White powder#>99% #1g,2g,5g#Store at -20°C#Potent multi-kinase and pan-BCR-ABL inhibitor
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