首页 >>> 产品目录 >>> 分子生物学 >>> 蛋白相关
仪表展览网 >>> 展馆展区 >>> Recombinant Human Angiostatin
> Recombinant Human Angiostatin

产品资料

Recombinant Human Angiostatin

Recombinant Human Angiostatin
  • 如果您对该产品感兴趣的话,可以
  • 产品名称:Recombinant Human Angiostatin
  • 产品型号:
  • 产品展商:XYbscience
  • 产品文档:无相关文档
简单介绍
Recombinant Human Angiostatin由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。Recombinant Human Angiostatin所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
产品描述

Recombinant Human Angiostatin

产品编号

产品名称

产品包装

产品价格

XY372-1mg

Recombinant Human Angiostatin

1mg

7801.00


Species

Gene ID

Accession

Source

Length

MW

Tag

Human

5340

P00747

E. coli

259aa

29.7kDa


About this Antibody

Name

Recombinant Human Angiostatin (Recombinant Human Angiostatin; rHuAngiostatin);重组人血管抑素

Synonyms

Plasminogen; PLG

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells in vitro and anti-angiogenesis in vivo is 5.5×105IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μM filtered concentrated solution in 20mM NaAc, pH5.5, 4% mannitol.

Endotoxin

Less than 1EU/μg of rHuAngiostatin as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Angiostatin, is a ~30kDa fragment of plasminogen that is encoded by the PLG gene in humans. It is produced, for example, bybautoproteolytic cleavage of plasminogen, involving extracellular disulfide bond reduction by phosphoglycerate kinase.bFurthermore, angiostatin can be cleaved from plasminogen by different metalloproteinases (MMPs), elastase, prostate-specific antigen (PSA), 13kDa serine protease, or 24kDa endopeptidase. Angiostatin is known to bind many proteins, especially to angiomotin and endothelial cell surface ATP synthase but also integrins, annexin II, C-met receptor, ng2 proteoglycan, tissuetype plasminogen activator, chondroitin sulfate proteoglycans, and CD26. It seems to involve inhibition of endothelial cell migration, proliferation and induction of apoptosis, but its mechanism of action is still unclear. Angiostatin is currently undergoing clinical trials for its use in anticancer therapy. Recombinant angiostatin is expressed in E. coli.

Amino Acid Sequence

VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLK GTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP

包装清单:

产品编号

产品名称

包装

XY372-10μg

Recombinant Human Angiostatin

10μg

XY372-50μg

Recombinant Human Angiostatin

50μg

XY372-100μg

Recombinant Human Angiostatin

100μg

XY372-1mg

Recombinant Human Angiostatin

1mg

-

说明书

1

保存条件:
       -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
       由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
       本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
       为了您的**和健康,请穿实验服并戴一次性手套操作。

 

产品留言
标题
联系人
联系电话
内容
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!
  • 温馨提示:为规避购买风险,建议您在购买前务必确认供应商资质与产品质量。
  • 免责申明:以上内容为注册会员自行发布,若信息的真实性、合法性存在争议,平台将会监督协助处理,欢迎举报
产品留言
标题
内容
联系人
联系电话
电子邮件
公司名称
联系地址
验证码
点击换一张
注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
2.如有必要,请您留下您的详细联系方式!