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Recombinant Rhesus Macaque IL-13

Recombinant Rhesus Macaque IL-13
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  • 产品名称:Recombinant Rhesus Macaque IL-13
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  • 产品展商:XYbscience
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简单介绍
Recombinant Rhesus Macaque IL-13由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细���因子或重组蛋白不会粘附于管壁。Recombinant Rhesus Macaque IL-13所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
产品描述

Recombinant Rhesus Macaque IL-13

产品编号

产品名称

产品包装

产品价格

XY5862-1mg

Recombinant Rhesus Macaque IL-13

1mg

27053.00


Species

Gene ID

Accession

Source

Length

MW

Tag

Rhesus Macaque

574325

Q864V6

E. coli

114aa

12.6kDa


About this Antibody

Name

Recombinant Rhesus Macaque IL-13 (Recombinant Rhesus Macaque Interleukin-13; rRhIL-13);重组恒河猴白细胞介素13

Synonyms

Interleukin-13; IL-13; IL13

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 5ng/ml, corresponding to a specific activity of >2.0×105IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, 3% trehalose.

Endotoxin

Less than 1EU/μg of rRhIL-13 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-13 (IL-13) is expressed by the IL13 gene and secreted by many cell types, especially T helper type 2 (Th2) cells. The high solution from of IL-13 reported to be a monomer with two internal disulfide bonds that contribute to a bundled four α-helix configuration. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1beta, TNF-alpha, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Mature rhesus IL-13 shares 94%, 58%, and 60% amino acid sequence identity with human, mouse and rat IL-13, respectively.

Amino Acid Sequence

SPSPVPRSTA LKELIEELVN ITQNQKAPLC NGSMVWSINL TAGVYCAALE SLINVSGCSA IEKTQRMLNG FCPHKVSAGQ FSSLRVRDTK IEVAQFVKDL LVHLKKLFRE GRFN

包装清单:

产品编号

产品名称

包装

XY5862-2μg

Recombinant Rhesus Macaque IL-13

2μg

XY5862-10μg

Recombinant Rhesus Macaque IL-13

10μg

XY5862-100μg

Recombinant Rhesus Macaque IL-13

100μg

XY5862-1mg

Recombinant Rhesus Macaque IL-13

1mg

-

说明书

1

保存条件:
       -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
       由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
       本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
       为了您的**和健康,请穿实验服并戴一次性手套操作。

 


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