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Recombinant Murine IFN-λ2/IL-28A

Recombinant Murine IFN-λ2/IL-28A
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  • 产品名称:Recombinant Murine IFN-λ2/IL-28A
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  • 产品展商:XYbscience
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简单介绍
Recombinant Murine IFN-λ2/IL-28A由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。Recombinant Murine IFN-λ2/IL-28A所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
产品描述

Recombinant Murine IFN-λ2/IL-28A

产品编号

产品名称

产品包装

产品价格

XY6141-1mg

Recombinant Murine IFN-λ2/IL-28A

1mg

15444.00


Species

Gene ID

Accession

Source

Length

MW

Tag

Mouse

330496

Q4VK74

E. coli

174aa

19.7kDa


About this Antibody

Name

Recombinant Murine IFN-λ2/IL-28A (Recombinant Murine Interferon-λ2/Interleukin-28A; rMuIFN-λ2/IL-28A)Recombinant Mouse IFN-λ2/IL-28A ; 重组小鼠干扰素λ2/白细胞介素28A

Synonyms

IFN-lambda 2; interleukin-28A; IL28A; IL-28A; interferon, lambda 2

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 3ng/ml, corresponding to a specific activity of >3.3×105IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, with 5% trehalose.

Endotoxin

Less than 0.1EU/μg of rMuIFN-λ2/IL-28A as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interferon lambda-2, as known as IL-28A, belongs to the lambda interferon family. IL-28A (IFN-λ2), IL-28B (IFN-λ3) and IL-29 (IFN-λ1) are type III interferons that are class II cytokine receptor ligands. These IFNs signal through a receptor complex consisting of IL10R2 (also called CRF2-4) and IFNLR1 (also called CRF2-12). Interferon lambda-2 displays potent antiviral activity and antitumor activity, so it plays a significant role in the antiviral immune defense in the intestinal epithelium. It also upregulate MHC class I antigen expression. Recombinant murine interferon lambda-2 contains 174 amino acids and it shares 81% and 66%a.a. sequence identity with rat and human IFN-λ2, respectively, and functions across species.

Amino Acid Sequence

DPVPRATRLP VEAKDCHIAQ FKSLSPKELQ AFKKAKDAIE KRLLEKDMRC SSHLISRAWD LKQLQVQERP KALQAEVALT LKVWENMTDS ALATILGQPL HTLSHIHSQL QTCTQLQATA EPKPPSRRLS RWLHRLQEAQ SKETPGCLED SVTSNLFRLL TRDLKCVASG DQCV

包装清单:

产品编号

产品名称

包装

XY6141-5μg

Recombinant Murine IFN-λ2/IL-28A

5μg

XY6141-20μg

Recombinant Murine IFN-λ2/IL-28A

20μg

XY6141-100μg

Recombinant Murine IFN-λ2/IL-28A

100μg

XY6141-1mg

Recombinant Murine IFN-λ2/IL-28A

1mg

-

说明书

1

保存条件:
       -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
       由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
       本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
       为了您的**和健康,请穿实验服并戴一次性手套操作。

 

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