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Recombinant Human GRO-γ/CXCL3

Recombinant Human GRO-γ/CXCL3
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  • 产品名称:Recombinant Human GRO-γ/CXCL3
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简单介绍
Recombinant Human GRO-γ/CXCL3由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋��不会粘附于管壁。Recombinant Human GRO-γ/CXCL3所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
产品描述

Recombinant Human GRO-γ/CXCL3

产品编号

产品名称

产品包装

产品价格

XY6497-1mg

Recombinant Human GRO-γ/CXCL3

1mg

15444.00


Species

Gene ID

Accession

Source

Length

MW

Tag

Human

2921

P19876

E. coli

73aa

7.9kDa


About this Antibody

Name

Recombinant Human GRO-γ/CXCL3 (Recombinant Human Growth Regulated Protein-γ/CXCL3; rHuGRO-γ/CXCL3);重组人生长调节致癌基因γ/CXCL3

Synonyms

CINC-2; Dcip1; Gm1960; GRO gamma; chemokine (C-X-C motif) ligand 3; CINC-2b; C-X-C motif chemokine 3; GRO3; GRO3 oncogene; GROg; GROG; GRO-gamma; GRO-gamma(1-73); Growth-regulated protein gamma; Macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma; MGSA gamma; MIP2B; MIP-2b; MIP2-beta; SCYB3

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected human 293 cells is in a concentration range of 10-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.4, 50mM NaCl.

Endotoxin

Less than 1EU/μg of rHuGRO-γ/CXCL3 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions.

Category

Chemokines

Background

CXCL3, also named GRO-γ, is belonging to the CXC chemokine family and encoded by the gene CXCL3. CXCL3/GRO-γ shares 86% amino acid sequence with CXCL1/GRO-α. All three human GROs (GRO-α, GRO-β, GRO-γ) are members of the intercrine alpha (chemokine C-X-C) subfamily of chemokines. This chemokine is secreted by monocytes and macrophages. The functional receptor for CXCL3 has been identified as CXCR2. Similar to other GRO proteins, CXCL3 is potent neutrophil attractants and activators. CXCL3 plays a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. All three GROs can bind with high affinity to the IL-8 receptor type B.

Amino Acid Sequence

ASVVTELRCQ CLQTLQGIHL KNIQSVNVRS PGPHCAQTEV IATLKNGKKA CLNPASPMVQ KIIEKILNKG STN

包装清单:

产品编号

产品名称

包装

XY6497-2μg

Recombinant Human GRO-γ/CXCL3

2μg

XY6497-10μg

Recombinant Human GRO-γ/CXCL3

10μg

XY6497-100μg

Recombinant Human GRO-γ/CXCL3

100μg

XY6497-1mg

Recombinant Human GRO-γ/CXCL3

1mg

-

说明书

1

保存条件:
       -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
       由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
       本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
       为了您的**和健康,请穿实验服并戴一次性手套操作。

 

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