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Recombinant Human MIC-A, His-tag

Recombinant Human MIC-A, His-tag
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  • 产品名称:Recombinant Human MIC-A, His-tag
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  • 产品展商:XYbscience
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简单介绍
Recombinant Human MIC-A, His-tag由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细���因子或重组蛋白不会粘附于管壁。Recombinant Human MIC-A, His-tag所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
产品描述

Recombinant Human MIC-A, His-tag

产品编号

产品名称

产品包装

产品价格

XY7145-1mg

Recombinant Human MIC-A, His-tag

1mg

12354.00


Species

Gene ID

Accession

Source

Length

MW

Tag

Human

100507436

Q29983

E. coli

320aa

36.9kDa

His


About this Antibody

Name

Recombinant Human MIC-A, His-tag (Recombinant Human MHC Class I PolypeptideRelated Sequence A, His-tag; rHuMIC-A, His-tag);重组人MIC类多肽相关序列AHis标签

Synonyms

FLJ60820; MGC111087; PERB11.1

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The specific activity is determined by binding MICA antibody in ELISA.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4, and 8 M Urea.

Endotoxin

Less than 1EU/μg of rHuMIC-A, His-tag as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water to a concentration of 1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at -20. Further dilutions should be made in appropriate buffered solutions, which contain 8M Urea.

Category

Others

Background

MIC-A (MHC class I chain-related gene A) is a single-pass type I member protein. It is expressed on the cell surface in gastric epithelium, endothelial cells and fibroblasts and in the cytoplasm in keratinocytes and monocytes. Additionally, MIC-A can be induced by bacterial and viral infections. It shares 85% amino acid identity with MIC-B and they are distantly related to the MHC class I proteins. Because they possess three extracellular Ig-like domains, but unlike classical MHC class I molecules. They do not form a heterodimer with beta2 microglobulin, but bind as a monomer to a KLRK1/NKG2D that is an activating receptor expressed on NK cells, NKT cells, γδ T cells, and CD8+ αβ T cells. Recognition of MICA by NKG2D results in the activation of cytolytic activity and/or cytokine production by these effector cells. MIC-A recognition plays an important role in tumor surveillance, viral infections, and autoimmune diseases.

Amino Acid Sequence

MSYYHHHHHH DYDIPTTENL YFQGAMAPEF EPHSLRYNLT VLSWDGSVQS GFLTEVHLDG QPFLRCDRQK CRAKPQGQWA EDVLGNKTWD RETRDLTGNG KDLRMTLAHI KDQKEGLHSL QEIRVCEIHE DNSTRSSQHF YYDGELFLSQ NLETKEWTMP QSSRAQTLAM NVRNFLKEDA MKTKTHYHAM HADCLQELRR YLKSGVVLRR TVPPMVNVTR SEASEGNITV TCRASGFYPW NITLSWRQDG VSLSHDTQQW GDVLPDGNGT YQTWVATRIC QGEEQRFTCY MEHSGNHSTH PVPSGKVLVL QSH KLGCFGG

包装清单:

产品编号

产品名称

包装

XY7145-10μg

Recombinant Human MIC-A, His-tag

10μg

XY7145-50μg

Recombinant Human MIC-A, His-tag

50μg

XY7145-100μg

Recombinant Human MIC-A, His-tag

100μg

XY7145-1mg

Recombinant Human MIC-A, His-tag

1mg

-

说明书

1

保存条件:
       -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以**配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
       由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
       本产品**于专业人员的科学研究用,不得用于临床诊断或**,不得用于食品或药品,不得存放于普通住宅内。
       为了您的**和健康,请穿实验服并戴一次性手套操作。

 

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