白细胞介素-2单克隆抗体
规格:1mg/1ml
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce 克隆类型:Monoclonal 亚型:IgG 纯化方法:affinity purified by Protein G **原:KLH conjugated synthetic peptide derived from human IL-2 交叉反应:Human, 白细胞介素-2单克隆抗体细胞定位:分泌型蛋白 产品介绍:background: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential 白细胞介素-2单克隆抗体role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008] Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Subcellular Location: Secreted. DISEASE: Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Similarity: Belongs to the IL-2 family. Gene ID: 3558 Database links: Entrez Gene: 3558 Human Entrez Gene: 16183 Mouse Entrez 白细胞介素-2单克隆抗体Gene: 116562 Rat Omim: 147680 Human SwissProt: P60568 Human SwissProt: P04351 Mouse SwissProt: P17108 Rat Unigene: 89679 Human Unigene: 14190 Mouse Unigene: 9871 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-2作为一种T细胞生长因子在**应答及其调节中起重要作用,IL-2的拮抗剂可用于同种移植排斥、T细胞性白血病以及某些自身**性**的**.胞内IL-2的水平是反映Th1 /Th2型细胞平衡状态的一个有用指标,血清IL-2的水平异常增高与某些**密切相关 白细胞介素-2单克隆抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 研究领域:**学 糖蛋白 储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. 来源: Mouse 外观: Lyophilized or Liquid 英文名: IL-2
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Monoclonal
亚型:IgG
纯化方法:affinity purified by Protein G
**原:KLH conjugated synthetic peptide derived from human IL-2
交叉反应:Human,
白细胞介素-2单克隆抗体细胞定位:分泌型蛋白
产品介绍:background: The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential 白细胞介素-2单克隆抗体role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008] Function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. Subcellular Location: Secreted. DISEASE: Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17. Similarity: Belongs to the IL-2 family. Gene ID: 3558 Database links: Entrez Gene: 3558 Human Entrez Gene: 16183 Mouse Entrez 白细胞介素-2单克隆抗体Gene: 116562 Rat Omim: 147680 Human SwissProt: P60568 Human SwissProt: P04351 Mouse SwissProt: P17108 Rat Unigene: 89679 Human Unigene: 14190 Mouse Unigene: 9871 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. IL-2作为一种T细胞生长因子在**应答及其调节中起重要作用,IL-2的拮抗剂可用于同种移植排斥、T细胞性白血病以及某些自身**性**的**.胞内IL-2的水平是反映Th1 /Th2型细胞平衡状态的一个有用指标,血清IL-2的水平异常增高与某些**密切相关
白细胞介素-2单克隆抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 糖蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Mouse
外观: Lyophilized or Liquid
别名: Interleukin-2; T-cell growth factor; Aldesleukin; IL 2; IL2; Interleukin 2; Interleukin2; Lymphokine; POIL2; T Cell Growth Factor; TCGF; IL2_HUMAN; Involved in regulation of T cell clonal expansion.
分子量: 15kDa