人乙型肝炎e抗原单克隆(包被)抗体
规格:1mg/1ml
英文名: HBeAg (2E9)
别名: Hepatitis B Virus E Antigen; HBe antigen; HBeAg; HBVgp4; Pre C,C; Precore protein; Precore/core; Precore/core ORF; Precore/core protei; HBEAG_HBVD3; External core antigen; HBeAg; p25.
分子量: 18kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Monoclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:HBeAg full length protein
交叉反应:Hepatitis B virus
人乙型肝炎e抗原单克隆(包被)抗体细胞定位:
产品介绍:background: Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen 人乙型肝炎e抗原单克隆(包被)抗体(anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful. Function: May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during ***** infections. Subunit: Homodimerizes. Subcellular Location: Secreted. Host nucleus. Post-translational modifications: Phosphorylated. Cleaved by 人乙型肝炎e抗原单克隆(包被)抗体host furin. Similarity: Belongs to the orthohepadnavirus precore antigen family. Gene ID: 944568 Database links: Entrez Gene: 944568 Hepatitis B virus SwissProt: Q89714 Hepatitis B virus Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 大量商议 (bsm-2023M,bsm-2022M)可用于双抗夹心。
人乙型肝炎e抗原单克隆(包被)抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:**学 **及病毒
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Mouse
外观: Lyophilized or Liquid