人脑钠素单克隆抗体
规格：1mg/1ml
英文名： BNP(H1G3)
别名： BNP 32; Brain natriuretic peptide 32; Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein.
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Monoclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human BNP
交叉反应：Human,
人脑钠素单克隆抗体细胞定位：
产品介绍：background: Brain natriuretic peptide (BNP) circulates in blood as a peptide hormone with natriuretic, vasodilatory and renin inhibitory properties. BNP is secreted predominantly by the left ventricular myocytes in response to volume expansion and pressure overload. BNP belongs to a family of structurally similar peptide hormones, which includes atrial natriuretic peptide (ANP), BNP, C-type natriuretic peptide (CNP) and urodilatin. These peptides are characterized by a common 17 amino acid ring structure with a disulfide bond between two cystein residues. 人脑钠素单克隆抗体This ring structure shows high homology between different natriuretic peptides (eleven of the 17 amino acid residues are homologous in the ring of each of the natriuretic peptides). BNP is a 32 amino acid peptide with disulfide bond between the cysteine residues Cys10 and Cys26. In earlier studies it has been demonstrated that BNP concentration in blood increases with the severity of congestive heart failure. 人脑钠素单克隆抗体Quantitative measurement of BNP in blood provides an objective indicator of congestive heart failure severity. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 脑钠素主要是心脏**，心脏作为***器官释放脑钠素，调解体液及电解质内环境的恒定性。 B型利钠肽（钠尿肽）（B－typenatriureticpeptide，BNP），又称脑钠素或脑钠肽，因其有排钠**、内皮非依赖性的血管平滑肌作用而具有降压、抗心肌纤维化、影响神经***系统等功效。 近来发现BNP在各种心血管**，尤其是心室功能不全、急性心肌梗死（ami）、高血压等**的诊断、**及预后等方面有重要意义，已引起临床工作者的高度重视。
人脑钠素单克隆抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Mouse
外观： Lyophilized or Liquid